New opportunities for bone remodelling thanks to biotechnology

When applied to health, biotechnology is offering ever more spectacular possibilities, as shown in the results of a new study called “N-Phenacylthiazolium Bromide Reduces Bone Fragility Induced by Nonenzymatic Glycation” carried out by biomedical engineers at the Rensselaer Polytechnic Institute in Troy (USA) and recently published in the scientific journal PLOS ONE.

The results of this study show that N-phenacylthiazolium bromide, or PTB, can dissolve impurities within bone tissue that cause the femur and other major bones in the body to become more fragile, so significantly increasing the risk of bone fractures. Deepak Vashishth, director of the Centre for Biotechnology and Interdisciplinary Studies and professor in the Department of Biomedical Engineering at the Rensselaer Polytechnic Institute, said “The recent findings are an important milestone on the path to our long-term goal of realizing a drug-based intervention for reducing age-related problems in bone tissue.” A look at how our bones work Bones change and are constantly Read more

Cleopatra Study improves overall survival rates for patients with HER2 positive breast cancer

Only a few years ago, being diagnosed with HER2 positive breast cancer meant surviving for no more than 20 months. Fortunately, new research such as that undertaken in the Cleopatra Study, has changed the outlook for one of the most virulent and deadly types of breast cancer which it is now one of the cancers with a more encouraging prognosis for the patient.

Today, a patient diagnosed with HER2 positive breast cancer in which the cancer cells contain the HER2 protein has up to a 90 percent chance of a cure as long as the cancer has not spread to other organs. Best Doctors’ experts confirm this positive outlook Dr Luis Costa, Director of Oncology at the Santa Maria Hospital, Lisbon (Portugal), Professor of Medicine and Biology of Cancer at Lisbon University and member of Best Doctors’ Medical Advisory Board, gives us his thoughts on the Cleopatra Study which focussed on research into using a combination treatment of Trastuzumab (Herceptin), chemotherapy and Pertuzumab (Perjeta) for Read more

Rediscovering grapefruit for better health

We very often do not completely realise how beneficial such a readily available food can be for our health. Recent tests carried out on animals have discovered that the natural ingredients in grapefruit, which are high in flavonoids, have properties, which are good for hypoglycemia (low blood sugar) in the intestine, which helps to metabolise glucose in the liver.

If this was not enough, it has also been shown that grapefruit have antioxidant and anti-inflammatory properties, which can be of great importance in our hard struggle against obesity and diabetes.

Dr de la Garza, from the Department of Food Science and Physiology of the Faculty of Pharmacy at the University of Navarra, has published the results of this research in her work Anti-obesity and anti-diabetic properties of two natural extracts rich in flavonoids (Helichrysum and Grapefruit): physiological and molecular mechanisms. Dr Martínez and Dr Milagro, from the department of Nutrition at the University of Navarra also collaborated in the research. These results have also been published in two prestigious scientific journals, Journal of Agricultural and Food Chemistry and Food & Function, so we can be reasonably optimistic about the effects of Read more