Cardiovascular risk of anti-inflammatories

In the last number of months the debate has intensified about the cardiovascular risks of anti-inflammatories such as aspirin, ibuprofen or paracetamol, which are among the best known of these drugs (NSAIDs: traditional nonspecific non-steriodal anti-inflammatory drugs and COX-2: selective inhibitors of cyclo-oxygenase-2).

Some recent publications have shed some light on this issue by way of different studies that have carried out research on the cardiovascular risks, and other types of risks in the administration of both types of anti-inflammatories.

Several studies that allow conclusions to be drawn The Finnish group, Helin-Salmivaara et al., kept track of more than 33,000 patients diagnosed with first myocardial infarction to test their association with the administration of these two types of anti-inflammatories. The results show that, although there was a moderate increase in the risk of first myocardial infarction with the use of either of these compounds, the risk was similar in both types of anti-inflammatories. Another recent study by Anderssohn et al., assessed the risk of ischaemic stroke in those of type COX-2 and concluded that this risk depends only on the individual properties Read more