Cystic Fibrosis: research improves treatment options

Cystic Fibrosis, also known by its initials, CF, is a genetic disease which develops in our sweat glands and mucous membranes and which can affect our vital organs, including the liver, lungs and pancreas.

The disease can be fatal, producing thick mucus which can give rise to severe breathing problems as well as the appearance of bacteria leading to serious lung complications. Recent research, however, has brought possible new treatments for the disease to light. Last June, a team of researchers from Queen’s University in Belfast (UK), developed a combination therapy which improves lung function and reduces the rate of hospitalization for patients with CF. Working with colleagues from the United States and Australia, the University’s Professor Stuart Elborn centered his research on two drugs: Ivacaftor and Lumacaftor. The study included over 1,100 CF patients. Up to Read more

Disease and genetic inheritance

Today we are going to comment on the Best Doctors Blog about the close relationship between some diseases and the genetic inheritance that parents pass on to their children through their genes.

It is safe to say that genes are the cornerstone of genetic inheritance, in so far as they contain our DNA, which in turn determines the instructions for making proteins in our body. Proteins carry out most of the functions within our cells: building structures, moving molecules and decomposing different types of toxins – to name but a few activities.

What is DNA? Deoxyribonucleic acid (abbreviated as DNA) is a nucleic acid whose content contains the genetic instructions used in the development of all living organisms that we know of. If we address the nature of the deoxyribonucleic acid molecule, we will find that its natural purpose is the long-term conservation of genetic information. As far as its structure is concerned, DNA takes the form of a double helix in which the information is stored as a code made up of four chemical bases: adenine (A), guanine (G), cytosine (C) and thymine (T). Now that we have learnt a little more about what Read more