Medical Breakthrough: First gene-editing in human

Chromosomes on blue background, scientific concept 3d illustration

Brian Madeux, 44, from Arizona, USA has been dealing with Hunter syndrome his entire life. He never expected to live past his early 20s and although he has surpassed his life expectancy, he experiences pain every second of the day.

A team of pioneering doctors in California proposed that Brian partake in an experimental trial that could change medical history forever. Brian was recently infused with the first gene-editing therapy directly in his bloodstream at Oakland's UCSF Benioff Children's Hospital. The Mayo Clinic classifies Hunter syndrome as “a very rare, inherited genetic disorder caused by a missing or malfunctioning enzyme. Because the body doesn't have enough of the enzyme to break down certain complex molecules, the molecules build up in harmful amounts. In Hunter syndrome, the buildup of massive amounts of these harmful substances eventually causes permanent, progressive damage affecting appearance, Read more